Gullainbarre syndrome gbs is one of these infrequent complications. Dengue and dengue hemorrhagic fever centers for disease. Since the second edition of dengue haemorrhagic fever. Dengue virus is prevalent throughout the tropics and subtropics. Dengue fever is a mosquitotransmitted arboviral infection mainly found in subtropical and tropical countries.
The mosquito aedes aegypti is the main vector of transmission of dengue virus in countries lying between latitudes 35 degrees north and 35 degrees south. Dengue fever is a disease spread by the aedes aegypti mosquito and is caused by one of four dengue viruses. Dengue fever is a viral infection that can cause lifethreatening illness, milder flulike illness, or no symptoms at all. This acute febrile illness can be a deadly infection in cases of severe manifestation, causing dengue hemorrhagic shock. Case presentation on dengue fever, dengue shock syndrome 2.
Pulmonary hemorrhage syndrome associated with dengue fever. Vitamin d serostatus and dengue fever progression to dengue. Classic dengue fever is primarily a disease of older children and adults. For this reason, some items on this page will be unavailable. Bangladesh experienced the first visible outbreak of dengue in 2000. Mild dengue fever causes a high fever, rash, and muscle and joint pain. Herran2 1department of epidemiology, university of michigan school of public health, ann arbor, mi, usa. It is a mosquitoborne flavivirus that belongs to the family flaviviridae, and consists of four distinct serotypes denv 14 1, 2.
National notifiable diseases surveillance system nndss note. Secondary forms of dengue fever are dengue hemorrhagic fever, and dengue shock syndrome. Dengue fever symptoms, diagnosis, treatments and causes. In 1998 this mosquitoborne disease is the most important. Dengue shock syndrome oxford medical case reports oxford. Feb 16, 2018 if severe, dengue fever can damage the lungs, liver or heart. Dengue fever is endemic in tropical and subtropical areas. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus. Chapter 1 epidemiology, burden of disease and transmission. Dengue fever vaccine, symptoms, treatment, prevention. Known also as dengue hemorrhagic fever dhf, it starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat, cough, nausea, vomiting, and abdominal pain. Treat the symptoms of dengue and see your healthcare provider.
Dengue virus is transmitted by female mosquitoes mainly of the species aedes aegypti and, to a lesser extent, a. Two of his other family members also had fever and were diagnosed as having dengue fever. Dec 01, 2012 dengue fever df, caused by dengue virus, is an arboviral disease characterized by an initial nonspecific febrile illness that can sometimes progress to more severe forms manifesting capillary leakage and hemorrhage dengue hemorrhagic fever, or dhf and shock dengue shock syndrome, or dss. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. National guidelines for clinical management of dengue. Dengue fever df is an acute infectious disease caused by dengue virus denv.
Dengue can also resemble endemic wnv fever and fleaborne murine typhus. All can cause syndromes that are selflimited or severe. Dengue pronounced dengee fever is a painful, debilitating mosquitoborne disease caused by any one of four closely related dengue viruses. Dengue shock syndrome an overview sciencedirect topics. Answer doctors can diagnose dengue infection with a blood test to check for the virus or antibodies to it. Pdf dengue fever, also known as breakbone fever, is a mosquitoborne infectious tropical disease caused by the dengue virus. Im pretty sure i had whats considered a mild case, but. From 1975 through 2009, symptomatic dengue virus infections were classified according to the who guidelines as dengue fever, dengue hemorrhagic fever dhf, and dengue shock syndrome the most severe form of dhf. Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of. This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Department of health and human services centers for. Dengue fever is a globally important arboviral infection transmitted by the aedes genus of mosquito primarily a aegypti, but also a albopictus, found in tropical and subtropical regions.
Denguehaemorrhagicfeverdengueshocksyndrome dhfdssisan enigmatic. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. A severe form of dengue fever, also called dengue hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure shock and death. Sep 15, 2015 the infection is now endemic in more than 100 countries, particularly the south east asia region, western pacific region, and the americas. Postdengue fatigue syndrome pdfs is not uncommon phenomenon of dengue viral infection. Clinical and serologic study of cuban children with dengue hemorrhagic feverdengue shock syndrome dhfdss. Dengue viral infections postgraduate medical journal.
Around the time the fever begins to subside usually 37 days after symptom onset, the patient may develop warning signs of severe disease. It is characterized by fever and mild constitutional symptoms to. The illness caused by dengue virus has been divided into four clinical spectrums. A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage bleeding and circulatory collapse shock. Javascript is disabled or is not supported by your browser. The case definition was changed to the 2009 clinical classification after reports that the case. Each year, an estimated 100 million cases of dengue fever and several hun dred thousand cases of dhf.
Dengue in the context of the imci i dengue, dengue haemorrhagic fever and dengue shock syndrome in the context of the integrated management of childhood illness department of child and adolescent health and development discussion papers on child health dengue in the context of the imci cah whofchcah05. Severe dengue, including dengue hemorrhagic fever or dengue shock syndrome, is characterized by severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums dengue is a mosquitoborne flavivirus found in tropical and subtropical regions of the world, mostly in urban and semiurban settings. Dengue is a viral disease transmitted by some types of mosquitoes. Vitamin d serostatus and dengue fever progression to dengue hemorrhagic feverdengue shock syndrome e. They are asymptomatic infection, acute febrile illness, classic dengue fever and dengue hemorrhagic fever including dengue shock syndrome. Dengue fever also known as breakbone fever, is a mosquitoborne topical disease caused by the dengue virus dengue fever, a benign syndrome caused by several arthropodborne viruses dengue fever.
One dengue fever vaccine, dengvaxia, is currently approved for use in those ages 9 to 45 who live in areas with a high incidence of dengue fever. However, you can still be infected with the other three viruses. The clinical presentations of dengue include nonspecific febrile illness, dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. Dengue is a mosquitoborne disease caused by one of the four serotypes of dengue viruses. Dengue fever nord national organization for rare disorders. Dengue chapter 4 2020 yellow book travelers health cdc. It is an acute illness of sudden onset that usually follows a benign course with symptoms such as headache, fever, exhaustion, severe muscle and joint pain, swollen lymph nodes lymphadenopathy, and rash. Dengue chapter 4 2020 yellow book travelers health. Dengue fever is a disease caused by a family of viruses transmitted by aedes mosquitoes symptoms of dengue fever include severe joint and muscle pain, swollen lymph nodes, headache, fever, exhaustion, and rash. Dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world. Symptoms include fever, headache, muscle and joint pains, and a. Dengue fever genetic and rare diseases information center. It is widespread across asia, the pacific, central and southern america and africa where these mosquitoes exist.
Feb 16, 2018 no specific treatment for dengue fever exists. Dengue and dengue hemorrhagic fever pubmed central pmc. Infection may be asymptomatic or present with a broad range of clinical manifestations including a mild febrile illness to a lifethreatening shock syndrome. Once you are infected with one of the dengue viruses, you will develop immunity to that. Dengue fever genetic and rare diseases information. Dengue haemorrhagic fever 12 chapter 2 clinical diagnosis dengue virus infections may be asymptomatic or may lead to undifferentiated fever, dengue fever df or dengue haemorrhagic fever dhf with plasma leakage that may lead to hypovolaemic shock dengue shock syndrome, dss figure 2. These viruses are related to the viruses that cause. Yes, dengue feverthe exoticsounding virus thats been nicknamed breakbone fever and described as a fate worse than death. Post dengue fatigue syndrome pdfs is not uncommon phenomenon of dengue viral infection. However, neurological complications arising from dengue infection is not common. Full blood count cbcfbcas a baseline,as well as to monitor progress of disease is most important tool. Dengue viruses serotypes dengue 1 to 4 are flaviviruses associated primarily with febrile illnesses and rash. The common severe syndromedengue haemorrhagic feverdengue shock syndrome dhfdssis characterised by sudden vascular permeability generated by cytokines released when t cells attack dengueinfected cells. Dengue fever, also known as breakbone fever, is a mosquitoborne infectious tropical disease caused by the dengue virus.
Description of the clinical picture of dengue hemorrhagic feverdengue shock syndrome dhfdss in adults. Dengue virus causes disease in humans, including dengue fever, dengue hemorrhagic fever dhf and dengue shock syndrome dss 1, 2. Centers for disease control and prevention cdc considers dengue fever to cause the majority of acute febrile illnesses in travelers returning to the u. In this paper, we have reported a case in which a 39yearold woman presented with a neurological complication of dengue infection without typical symptoms and signs of dengue fever.
In addition, the symptoms of dengue fever, such as fever and body aches, closely resemble symptoms of influenza. Dengue fever usually presents as an acute fever with headache, rash, myalgia, retroorbital pain, arthralgia, prostration, lymphadenopathy, and leucopenia 8, 9. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito. Focusing on the serious form of dengue, the forms with overt bleeding dengue hemorrhagic fever and shock dengue shock syndrome are classified as dengue with high severity. Call your doctor right away if you develop any of the following. Dengue fever df, caused by dengue virus, is an arboviral disease characterized by an initial nonspecific febrile illness that can sometimes progress to more severe forms manifesting capillary leakage and hemorrhage dengue hemorrhagic fever, or dhf and shock dengue shock syndrome, or. Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity the cocirculation of multiple serotypes, and the emergence of dengue hemorrhagic fever in new geographic regions. As the disease spreads to new geographical areas, the frequency of the outbreaks has increased along with a. These forms of the disorder primarily affect children between 3 and 6 years of age who have been infected a second time with dengue virus, and infants 7 to 8 months of age. It is characterized by the sudden onset of fever and a variety of nonspecific signs and symptoms, including frontal headache, retroorbital pain, body aches, nausea and vomiting, joint pains, weakness, and rash 1, 71, 1, 6, 149. The pdfs has wide spectrum of musculoskeletal and neurological features. Dengue hemorrhagic fever dengue shock syndrome may resemble bacterial sepsis, e.
Dengue fever is estimated by the world health organization who to cause about 50100 million infections per year worldwide. Dengue fever is a mosquitoborne arthropodborne viral arboviral tropical disease in humans affecting 50528 million people worldwide. Vitamin d serostatus and dengue fever progression to. Comprehensive guideline for prevention and control of dengue. Blood pressure can drop to dangerous levels, causing shock and, in some cases, death. Dengue fever also known as breakbone fever, is a mosquitoborne topical disease caused by the dengue virus dengue fever, a benign syndrome. The most common hemorrhagic manifestations are mild and include a positive tourniquet test, skin hemorrhages petechiae, hematomas, epistaxis nose bleed, gingival bleeding gum bleed, and microscopic hematuria. As the disease spreads to new geographical areas, the frequency of the outbreaks is increasing. Once you are infected with one of the dengue viruses, you will develop immunity to that virus for the rest of your life. Symptoms typically begin three to fourteen days after infection. Physical examination was remarkable for tachycardia pulse 110min, fever 102.
The presence of fever, rash, and headache the dengue triad is characteristic of dengue fever. Dengue outbreaks occur each year in north queensland following cases imported from overseas. Thyroid was swollen, warm and tender and patient had painful deglutition. The infection is endemic in more than 100 countries, particularly the south east asia region, western pacific region, and the americas. In recent decades, the number of new cases of dengue has increased. Dengue hemorrhagic fever dengue shock syndrome dhfdss is considered to be an antibodymediated viral disease, although this hypothesis remains speculative since the pathogenesis of dhfdss is not well understood. Dengue may be confused with zika or chikungunya infection in travelers returning from areas endemic for or experiencing outbreaks of those viruses. Your doctor may recommend that you drink plenty of fluids to avoid dehydration from vomiting and a high fever. Dengue virus is a singlestranded, enveloped rna virus and has four serotypes identified up to now, numbered 14. A diagnosis of dengue fever can easily be missed or delayed in temperate or northern areas of the world, such as the u. An acute suddenonset viral disease, dengue is transmitted by aedes mosquitoes. Dengue fever is a serious influenzalike illness, capable of advancing and leading to a fatal complication called severe dengue formerly referred to as dengue hemorrhagic fever. Dengue hemorrhagic fever can occur when someone is bitten by a mosquito or exposed to blood infected with the dengue virus.
The four dengue viruses are transmitted in tropical countries that circle the globe. Comprehensive guideline for prevention and control of. Health experts have known about dengue fever for more than 200 years. Dengue fever is a disease caused by a family of viruses transmitted by infected mosquitoes. If you think you have dengue pdf icon pdf 1 page see a healthcare provider if you develop a fever or have symptoms of dengue. Dengue fever symptoms, causes, contagious, rash, prevention. Dengue viruses can be grouped into four antigenically distinct types based on serological typing. The disease is widespread throughout the tropics, with local variations in risk influenced by rainfall, temperature and unplanned rapid urbanization. While recovering from dengue fever, watch for signs and symptoms of dehydration. Known also as dengue hemorrhagic fever dhf, it starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat. Aug 31, 2015 however, neurological complications arising from dengue infection is not common. The acute abdominal complications of dengue fever are acute appendicitis, acute pancreatitis, acute acalculous cholecystitis and nonspecific peritonitis.
Dengue is a febrile illness caused by infection with one of four dengue viruses denv transmitted by aedes aegypti or aedes albopictus mosquitoes during the taking of a blood meal. Dengue and dengue hemorrhagic fever clinical microbiology. Dengue is a mosquitoborne disease caused by any one of four closely related dengue viruses. Dengue hemorrhagic fever and dengue shock syndrome some patients with dengue fever go on to develop dengue hemorrhagic fever dhf, a severe and sometimes fatal form of the disease.